CCL5 anticorps

N° du produit ABIN400758

Cet anticorps anti-CCL5 est un anticorps Souris Monoclonal détectant CCL5 dans Neut, EIA et IHC (p). Adapté pour Humain.

Aperçu rapide pour CCL5 anticorps (ABIN400758)

Antigène: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL5 est non-conjugé

Application: Neutralization (Neut), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8-PP-11

Détail du produit anti-CCL5 anticorps

Specificité: Recognizes Human RANTES. The antibody effectively inhibits Chemotaxis of Human Monocytes, Human Lymphocytes and Rat peritoneal Macrophages induced by Human RANTES.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: C-C motif chemokine 5, D17S136E, SCYA5, Small-inducible cytokine A5, SIS-delta, EoCP,T-cell-specific protein RANTES, cell-specific protein P228, Eosinophil-chemotactic cytokine

Purification: Protein A Chromatography.

Immunogène: RANTES

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 2-4 μg/mL. Neutralization. Immunohistochemistry on Paraffin Sections: 5 μg/mL. This CCL5 antibody was validated for use in Immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) Human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by AlkalinePhosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 40 % Glycerol without preservatives.

Agent conservateur: Without preservative

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CCL5

Antigène: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Autre désignation: RANTES / CCL5

Sujet: RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.Synonyms: C-C motif chemokine 5, D17S136E, E °CP, Eosinophil-chemotactic cytokine, SCYA5, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES, cell-specific protein P228

ID gène: 6352

UniProt: P13501

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration